
IRC § 280E and the Psychedelic Industry: Tax Risks and Mitigation Strategies
Justin Botillier is the CEO of Calyx CPA LLC, a national accounting and advisory firm specializing in the cannabis and psychedelic industries. He has more than 20 years of experience advising small business owners and over a decade specializing in cannabis taxation, helping businesses navigate complex tax issues, including IRC § 280E.
Psychedelics are gaining medical and regulatory legitimacy, but federal tax law has not kept pace. While Oregon and Colorado regulate psilocybin services and additional states are considering similar programs, most psychedelics remain Schedule I substances, making IRC § 280E a significant tax issue. Learn who is affected, the risks involved, and practical strategies to legally mitigate 280E.